Chronic tinnitus and unipolar brush cell alterations in the cerebellum and dorsal cochlear nucleus
نویسندگان
چکیده
منابع مشابه
Somatic (craniocervical) tinnitus and the dorsal cochlear nucleus hypothesis.
PURPOSE Of all nonauditory sensory systems, only the somatosensory system seems to be related to tinnitus (eg, temporomandibular joint syndrome and whiplash). The purpose of this study is to describe the distinguishing characteristics of tinnitus associated with somatic events and to use these characteristics to develop a neurological model of somatic tinnitus. MATERIALS AND METHODS Case seri...
متن کاملDorsal cochlear nucleus hyperactivity and tinnitus: are they related?
PURPOSE Eight lines of evidence implicating the dorsal cochlear nucleus (DCN) as a tinnitus contributing site are reviewed. We now expand the presentation of this model, elaborate on its essential details, and provide answers to commonly asked questions regarding its validity. CONCLUSIONS Over the past decade, numerous studies have converged to support the hypothesis that the DCN may be an im...
متن کاملHyperactivity in the dorsal cochlear nucleus : Evolution of a chronic tinnitus model
Coffee and light refreshments will be provided at the session breaks. Posters should remain in place for all of Monday and Tuesday. Discussion time is scheduled during the meeting. In addition, a limited amount of space for the presentation of posters is possible on Wednesday. The size of poster boardse is 1.5m wide x 1m high. The poster display areas will be in the atrium and meeting rooms nea...
متن کاملElevated fusiform cell activity in the dorsal cochlear nucleus of chinchillas with psychophysical evidence of tinnitus.
Chinchillas with psychophysical evidence of chronic tinnitus were shown to have significantly elevated spontaneous activity and stimulus-evoked responses in putative fusiform cells of the dorsal cochlear nuclei (DCN). Chinchillas were psychophysically trained and tested before and after exposure to a traumatic unilateral 80 dB (sound pressure level) 4 kHz tone. Before exposure, two groups were ...
متن کاملThe dorsal cochlear nucleus as a participant in the auditory, attentional and emotional components of tinnitus.
The dorsal cochlear nucleus (DCN) has been modeled in numerous studies as a possible source of tinnitus-generating signals. This hypothesis was originally developed on the basis of evidence that the DCN becomes hyperactive following exposure to intense noise. Since these early observations, evidence that the DCN is an important contributor to tinnitus has grown considerably. In this paper, the ...
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ژورنال
عنوان ژورنال: Hearing Research
سال: 2017
ISSN: 0378-5955
DOI: 10.1016/j.heares.2017.04.016